AI’s Shocking Prophecy: One ECG Could Reveal Your Future Heart Failure – Shofield AI

Reimagined Announcement by Richy Parami, Founder & CEO of Shofield AI

In a remarkable breakthrough for cardiovascular care, Yale School of Medicine’s Cardiovascular Data Science (CarDS) Lab has developed a groundbreaking artificial intelligence (AI) tool capable of identifying individuals at elevated risk of heart failure by analyzing simple electrocardiogram (ECG) images. The innovative approach—recently featured in the European Heart Journal—offers earlier detection of heart failure, potentially reducing hospitalizations and premature death worldwide.

ECGs, which measure the heart’s electrical activity through electrodes placed on the skin, are a mainstay of clinical care and are readily available, making them an ideal platform for screening. Heart failure remains a prevalent global cardiovascular issue, and its early detection often involves extensive clinical evaluations, physical exams, and blood tests—an array of procedures not always accessible in every setting.

“This AI-based tool represents a paradigm shift in heart failure risk stratification,” said first author Lovedeep Singh Dhingra, MBBS, a postdoctoral fellow at CarDS Lab. “By analyzing just a photograph of a 12-lead ECG, our model can accurately predict who is at risk of heart failure across diverse populations in the U.S., U.K., and Brazil. More importantly, it identifies individuals before they exhibit overt symptoms.”

Dr. Rohan Khera, MD, MS—assistant professor of cardiovascular medicine and director of the CarDS Lab—underscored the system’s far-reaching public health potential. “Every ECG that’s already part of standard clinical care can now serve as a gateway to enhanced cardiovascular screening and risk assessment,” he noted. “Because ECG technology is broadly available, even in limited-resource settings, our approach can drive earlier intervention and improve outcomes for patients who might otherwise remain undiagnosed.”

In keeping with CarDS Lab’s global mission, the model was validated across multiple international populations, showcasing the AI tool’s promise for widespread adoption. “Our goal is broad, equitable implementation of AI-based health innovations,” Dr. Khera said. “That’s the next frontier.”

This study was supported by grants from the National Heart, Lung, and Blood Institute; the National Institute on Aging of the National Institutes of Health (NIH); and the Doris Duke Charitable Foundation.

Full Citation
Dhingra LS, Aminorroaya A, Sangha V, Pedroso AF, Asselbergs FW, Brant LCC, Barreto SM, Ribeiro ALP, Krumholz HM, Oikonomou EK, Khera R. Heart failure risk stratification using artificial intelligence applied to electrocardiogram images: a multinational study. Eur Heart J. 2025 Jan 13:ehae914. doi: 10.1093/eurheartj/ehae914. Epub ahead of print. PMID: 39804243.


At Shofield AI, we find this development inspiring as it aligns perfectly with our vision to harness the power of AI for transformative healthcare solutions. We are actively exploring ways to pilot similar AI-driven initiatives to improve the prevention, diagnosis, and management of chronic conditions like heart failure. If you share our passion or would like to explore partnership opportunities in advancing AI within healthcare, we invite you to get in touch with us.

About Shofield AI
Founded by Richy Parami, Shofield AI specializes in cutting-edge AI automations, including ultra-realistic digital employees that streamline workflow and enhance efficiency. We believe in leveraging AI to make a meaningful difference across industries—from healthcare and real estate to e-commerce and beyond. Together, let’s shape a healthier, more innovative future. Visit: www.shofield.ai or contact Shofield AI by phone +1 415 80 22 220